Our paper entitled “Tailored polyethylene glycol grafting on porous nanoparticles for enhanced targeting and intracellular siRNA delivery” has been published in Nanoscale as an inside front cover. In this study, we proposed a secondary packaging method on mesoporous surface of nanoparticles ensuring high drug loading capacity while preventing protein corona formation for target receptor recognition and intracellular delivery of siRNA (and other therapeutic agents as well). Surface chemistry always matters in drug delivery!