Our collaboration work on long-lived phosphorescence of silica nanoparticles with Profs. Woosung Kwon (Sookmyung Women’s University) and Kyeonghak Kim (Hanyang University) has been published in Chemical Engineering Journal. This work reports a use of defect-engineered silica nanoparticle that presents room-temperature phosphorescence with extended lifetime up to a few milliseconds-scale. Such a long lifetime allows tissue […]

Our collaborative work on biodegradable nanoparticles and controlled ferroptosis has been published in Nano Today. This work reports spatiotemporal tracking of intracellular nanoparticles using multimodal imaging systems including super-resolution microscopy and fluorescence correlation spectroscopy to reveal the ultimate fate of single nanoparticles upon autophagic clearance. Moreover, this study showed controlled ferroptosis upon triggered reduction of […]

A collaborative work with Prof. Hee Ho Park’s lab at Hanyang University for enhanced tissue regeneration using human serum albumin-based protein nanoparticles has been published in Journal of Nanobiotechnology:https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-023-02053-4 In this work, we report significantly improved would healing performance by using human serum albumin-mediated nanoparticle formulation with soluble bFGF. A systematic investigation both in vitro […]

Our collaborative study with Prof. Tae-Eun Park on brain delivery systems for treatment of Alzheimer’s disease has been published in ACS Nano. In this study, we have utilized the microphysiological systems (MPS) mimicking human blood-brain barrier on a chip to discover BBB-penetrating aptamers. The MPS-derived aptamers showed remarkable BBB penetration efficiency, led by clathrin-mediated transcytosis. […]

Our paper entitled “Tailored polyethylene glycol grafting on porous nanoparticles for enhanced targeting and intracellular siRNA delivery” has been published in Nanoscale as an inside front cover. In this study, we proposed a secondary packaging method on mesoporous surface of nanoparticles ensuring high drug loading capacity while preventing protein corona formation for target receptor recognition […]

A review article on the delivery systems for CRISPR-based genome editing is published in Biomedical Engineering Letters. This article provides an overview on essential elements in CRISPR/Cas systems and nanoparticle-based delivery carriers as an alternative method over viral vectors. Read the article here. Great job, Aaron and Minjong!

Prof. Jinmyoung Joo wrote a book chapter on Diagnostic and Therapeutic Nanomedicine in Advanced Imaging and Bio Techniques for Convergence Science, as a part of Advances in Experimental Medicine and Biology. This chapter provides in-depth understanding on nanotechnology, particularly in biomedical applications, including general concepts and recent advances of nanomedicine for clinically relevant diagnostics and […]

A floating magnetic membrane for efficient separation and enrichment of pathogenic bacteria using superparamagnetic nanoparticles and capillary glass tube has been developed. The virtual ‘filter’ can rapidly and selectively capture the target bacteria under continuous flow. This technology can be further expanded for large scale separation and purification of biological components. Watch out more.

Our collaborative study on fluorescence-based intracellular imaging with Prof. Kyo Han Ahn (POSTECH) has been accepted for publication in Chemical Communications. This work reports a discrepancy of fluorescent properties between solutions and intracellular environment. Along with this finding, we have developed a series of benzocoumarin dyes which has environment-insensitive characteristics for super-bright bioimaging.

A research article entitled “Luminescent silicon nanoparticles for distinctive tracking of cellular targeting and trafficking” has been accepted in Faraday Discussions. This paper is a part of the contribution to Faraday Discussions meeting organized by Royal Society of Chemistry. Prof. Joo will give an invited talk in the meeting held in York, UK.